Othmane Aouane


Modeling and simulation of the motion of 2D deformable interfaces in a confined geometry


Vesicles are extensively used as a model for understanding dynamics and deformation of red blood cells at the individual level but also regarding collective phenomena and rheology. We investigate numerically several kind of problems such as: (i) the dynamics of isolated cells; (ii) the hydrodynamic coupling between the red blood cells (by using vesicles as a model) subject to a Poiseuille flow under different confinements; (iii) the aggregation of red blood cells and formation of rouleaux; and (iv) the contribution of macromolecules in the formation of clusters under flow condition. The obtained results give a new insight into the physics of deformable objects under confinement that are transposable to the flow of red blood cells in the microcirculation.


F. Zakham*, O. Aouane*, et al.
Computational genomics-proteomics and Phylogeny analysis of twenty one mycobacterial genomes (Tuberculosis & non Tuberculosis strains).
Microb Inform Exp 2.1 (2012):7

A. Farutin, O. Aouane, and C. Misbah.
Vesicle dynamics under weak flows: Application to large excess area.
Physical Review E 85.6 (2012): 061922

O. Aouane, ..., C. Wagner and C. Misbah
Vesicle dynamics in a confined Poiseuille flow: From steady state to chaos.
Physical Review E 90.3 (2014):033011

M. Brust*, O. Aouane*, ..., C. Misbah and C. Wagner.
The plasma protein fibrinogen stabilizes clusters of red blood cells in microcapillary flows.
Scientific reports 4 (2014)

V. Claveria, O. Aouane, ..., M. Abkarian, C. Misbah and C. Wagner.
Clusters of red blood cells in microcapillary flow: hydrodynamic versus macromolecule induced interaction
Soft Matter (2016)

O. Aouane, ..., C. Wagner and C. Misbah
Hydrodynamic pairing of deformable vesicles in a confined flow.
Submitted to PRF

D. Flormann*, O. Aouane*, T. Podgorski*,..., C. Misbah and C.Wagner.
Contact zones of small and large red blood cell clusters from low to high dextran and fibrinogen concentrations.
In preparation.

*: equal contribution